Image of the Month

Damavand, the highest Asian inactive volcano in the Alborz mountains, around 66 km in the northeastern Tehran, Iran (the highest elevation is 5,671 m) (Photo by M. H. Azizi MD, Winter 2015).

A winter view of Abali, around 57 km in the northeastern Tehran, Iran (Photo by M. H. Azizi MD, 2015).


Announcement

The collection of articles appearing in the current book consists of manuscripts on the history of medicine in Iran, initially published from 1998 to 2014 in the “Archives of Iranian Medicine” (AIM). These articles are categorized into four separate parts, based on their subjects: Part 1) Ancient Times, Medieval Period, Part 2) Contemporary Medicine, Part 3) Outstanding Physicians and Part 4) Historical Background of Fatal Diseases in Iran. These 73 manuscripts have now been compiled in a 446 pages book for those who are interested in the history of Iranian medicine.more

Since the Archive of Iranian Medicine (AIM) journal presents as Open Access monthly, online periodical from May 2013, thus dear readers may refer to the journal website (www.aimjournal.ir) for free downloading of the published papers.

AIM Office


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A Monthly Peer-Reviewed Medical Journal Published by the Academy of Medical Sciences of the I.R. Iran; Indexed in PubMed/MEDLINE, ISI Web of Science, EMBASE, SCOPUS, CINHAL, PASCAL, CSA, SID, ISSN: Print 1029-2977, Online 1735-3947.The impact factor of Archives of Iranian Medicine according to Journal Citation Reports®(JCR®) 2012 is 1.222.

Announcement
Dear Readers;

The Archives of Iranian Medicine Journal will not accept case reports from March 2015 until December 2016.

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Selected Article
The Combined Effects of Healthy Lifestyle Behaviors on All-Cause Mortality: The Golestan Cohort Study 1

Authors’ affiliations:1Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran, 2Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland ,USA, 3Surveillance and Health Services Research, American Cancer Society, Atlanta, USA, 4Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran, 5Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran,  Iran, 6Department of Public Health Analysis, School of Community Health and Policy, Morgan State University, Baltimore, Maryland, USA, 7Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA, 8Departments of Oncology and Public Health and Primary Care, University of Cambridge, UK, 9International Prevention Research Institute, Lyon, France, 10The Tisch Cancer Institute and Institute for Translational Epidemiology, Mount Sinai School of Medicine, New York, USA, 11Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular -Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran, 12Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran, 13Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran, 14Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.

•Corresponding author and reprints: Ahmad Esmaillzadeh PhD, Department of Community Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran, P. O. Box: 81745-151. Tel: +98-311-792-2720, E-mail:esmaillzadeh@hlth.mui.ac.ir.

Reza Malekzadeh MD, Shariati Hospital, North Kargar St. Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran, P. O. Box: 14117–13135. Tel: +98-21-82415169

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Authors: Akbar Fazel-tabar Malekshah1, Marsa Zaroudi2, Arash Etemadi3, Farhad Islami4, Sadaf Sepanlou5, Maryam Sharafkhah6, Abbas-Ali Keshtkar7, Hooman Khademi8, Hossein Poustchi9, Azita Hekmatdoost10, Akram Pourshams11, Akbar Feiz Sani12, Elham Jafari13, Farin Kamangar14, Sanford M Dawsey15, Christian C Abnet16, Paul D Pharoah17, Paul J Berennan18, Paolo Boffetta19, Ahmad Esmaillzadeh20,
 
Keywords: Alternative healthy eating index, Golestan cohort study, life style score, mortality

 BACKGROUND: Most studies that have evaluated the association between combined lifestyle factors and mortality outcomes have been conducted in populations of developed countries.

Objectives: The aim of this study was to examine the association between combined lifestyle scores and risk of all-cause and cause-specific mortality for the first time among Iranian adults.
METHODS: The study population included 50,045 Iranians, 40 – 75 years of age, who were enrolled in the Golestan Cohort Study, between 2004 and 2008. The lifestyle risk factors used in this study included cigarette smoking, physical inactivity, and Alternative Healthy Eating Index. The lifestyle score ranged from zero (non-healthy) to 3 (most healthy) points. From the study baseline up to analysis, a total of 4691 mortality cases were recorded. Participants with chronic diseases at baseline, outlier reports of calorie intake, missing data, and body mass index of less than 18.5 were excluded from the analyses. Cox regression models were fitted to establish the association between combined lifestyle scores and mortality outcomes. 
RESULTS: After implementing the exclusion criteria, data from 40,708 participants were included in analyses. During 8.08 years of follow-up, 3,039 cases of all-cause mortality were recorded. The adjusted hazard ratio of a healthy lifestyle score, compared with non-healthy lifestyle score, was 0.68 (95% CI: 0.54, 0.86) for all-cause mortality, 0.53 (95% CI: 0.37, 0.77) for cardiovascular mortality, and 0.82 (95% CI: 0.53, 1.26) for mortality due to cancer. When we excluded the first two years of follow up from the analysis, the protective association between healthy lifestyle score and cardiovascular death did not change much 0.55 (95% CI: 0.36, 0.84), butthe inverse association with all-cause mortality became weaker 0.72 (95% CI: 0.55, 0.94), and the association with cancer mortality was non-significant 0.92 (95% CI: 0.58, 1.48). In the gender-stratified analysis, we found an inverse strong association between adherence to healthy lifestyle and mortality from all causes and cardiovascular disease in either gender, but no significant relationship was seen with mortality from cancer in men or women. Stratified analysis of BMI status revealed an inverse significant association between adherence to healthy lifestyle and mortality from all causes, cardiovascular disease and cancer among non-obese participants. 
CONCLUSION: We found evidence indicating that adherence to a healthy lifestyle, compared to non-healthy lifestyle, was associated with decreased risk of all-cause mortality and mortality from cardiovascular diseases in Iranian adults.
 
ISSN:1029-2977       Article type:Original
  
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