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Arch Iran Med. 2016;19(9): 0-0.
PMID: 27631184
Scopus ID: 84987622040
  Abstract View: 762
  PDF Download: 469

Case Report

Multi-Target Approach to Metastatic Adrenal Cell Carcinoma

Norasyikin A Wahab * , Suehazlyn Zainudin, Aini AbAziz, Norlaila Mustafa, Norlela Sukor, Nor Azmi Kamaruddin

Abstract

Adrenal cell carcinoma is a rare tumor and more than 70% of patients present with advanced stages. Adrenal cell carcinoma is an aggressive tumor with a poor prognosis. Surgical intervention is the gold standard treatment and mitotane is the only drug approved for the treatment of adrenal cell carcinoma. Until recently in 2012, the etoposide, doxorubicin, cisplatin plus mitotane are approved as first-line therapy based on response rate and progression-free survival.

This case illustrates a case of advanced adrenal cell carcinoma in a young girl who presented with huge adrenal mass with inferior vena cava thrombosis and pulmonary embolism. Multi-approach of therapy was used to control the tumor size and metastasis. Therefore, it may prolong her survival rate for up to 5 years and 4 months.

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ePublished: 01 Sep 2016
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