Arch Iran Med. 2012;15(5): 303-305.
PMID: 22519380
Scopus ID: 84875585241
  Abstract View: 501
  PDF Download: 350

Original Article

Severe Thrombocytopenia and Hemorrhagic Diathesis due to Brucellosis

Hasan Karsen * , Fazilet Duygu, Kubilay Yapıcı, Ali İrfan Baran, Huseyin Taskıran, İrfan Binici


BACKGROUND: We aimed to examine cases of brucellosis that presented with severe thrombocytopenia and hemorrhagic diathesis.
METHODS: A total of 10 brucellosis cases with severe thrombocytopenia were included in this case-series study. Patients’ files were reviewed for their clinical and laboratory findings, as well as clinical outcomes and complications. Platelet counts of < 20000/mm³ were diagnosed as severe thrombocytopenia.
RESULTS: The lowest thrombocyte count was 3000/mm³ while the highest was 19000/mm³ (mean: 12000/mm³). Patients had the following symptoms: epistaxis (7 cases), petechia with epistaxis (4 cases), bleeding gums (3 cases), ecchymosis with epistaxis (2 cases), melena and renal failure (2 cases), and hematuria (1 case). Patients were given rifampicin and doxycycline along with supportive hematological therapy. All were treated successfully with no evidence of recurrence at follow-up visits.
CONCLUSION: Since brucellosis is endemic in developing countries, it must be considered in the differential diagnosis of cases that present with severe thrombocytopenia and hemorrhagic diathesis.

First Name
Last Name
Email Address
Security code

Abstract View: 501

Your browser does not support the canvas element.

PDF Download: 350

Your browser does not support the canvas element.

ePublished: 01 May 2012
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)