Arch Iran Med. 2019;22(4):174-181.
  Abstract View: 28
  PDF Download: 41

Original Article

Serum Levels of Vitamin D, Retinol and Zinc in Relation to overweight among Toddlers: Findings from a National Study in Iran

Yaser Sharif 1,2, Omid Sadeghi 1,2, Ahmadreza Dorosty 2, Fereydoun Siassi 2, Mahmood Jalali 2, Abolghasem Djazayery 2, Kazem Mohammad 3, Mahboobeh Parsaeian 3, Zahra Abdollahi 4, Ramin Heshmat 5, Amirhusein Yarparvar 6, Hamed Pouraram 2 * , Ahmad Esmaillzadeh 2,7,8 *

1 Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
3 School of Public Health, Tehran University of Medical Sciences (TUMS), Tehran, Iran
4 Nutrition Department, Under-secretary for Health, Ministry of Health & Medical Education, Tehran, Iran
5 Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences (TUMS), Tehran, Iran
6 Health and Nutrition Unit, UNICEF Iran, Tehran
7 Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
8 Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding Authors: Hamed Pouraram, PhD; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Phone: +98-21-88955805; Fax: +98-21-88984861; Email: h-pouraram@tums.ac.ir ; Ahmad Esmaillzadeh PhD, Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Phone: +98-21-88955805; Fax: +98-21-88984861; email: esmaillzadeh@hlth.mui.ac.ir Email: a.esmaillzadeh@gmail.com

Abstract

Background: Some studies have examined the association between micronutrient deficiencies and overweight in children, but data in this regard are conflicting. This study was done to investigate the association between serum levels of vitamin D, A and zinc with overweight in a large sample of Iranian toddlers.

Methods: A total of 4261 toddlers, aged 15-23 months, who had an Iranian birth certificate and attended primary health care, were included in the current cross-sectional study. Weight and height were measured by experts based on standard protocols and body mass index (BMI) was calculated. Based on WHO criteria, overweight was defined as BMI-z-score of ≥1SD. Serum levels of 25(OH)D3 , retinol and zinc were measured for each toddler. Binary logistic regression was applied to assess the association of 25(OH)D3 , retinol and zinc levels with overweight.

Results: Mean age of study participants was 19.2 ± 8.4 months. After controlling for potential confounders, children in the highest quartile of serum 25(OH)D3 levels had lower odds of overweight compared with those in the lowest quartile (OR: 0.79, 95% CI: 0.63–0.99). Furthermore, a marginally significant inverse association was found between serum levels of 25(OH)D3 and overweight among urban toddlers (OR: 0.75, 95%CI: 0.56–1.00). Such a relationship was not seen for rural children. No other significant association was seen between serum levels of retinol and zinc and overweight either before or after controlling for covariates.

Conclusion: In conclusion, we found a significant inverse association between serum levels of vitamin D and overweight among toddlers. Further studies, particularly of prospective nature, are required to confirm our findings.

Cite this article as: Sharif Y, Sadeghi O, Dorosty A, Siassi F, Jalali M, Djazayery A, et al. Serum levels of vitamin d, retinol and zinc in relation to overweight among toddlers: findings from a national study in Iran. Arch Iran Med. 2019;22(4):174–181.
First name
 
Last name
 
Email address
 
Comments
 
Security code


Article Viewed: 28

Your browser does not support the canvas element.


PDF Downloaded: 41

Your browser does not support the canvas element.

Submitted: 18 May 2018
Accepted: 13 Feb 2019
First published online: 01 Apr 2019
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - FireFox Plugin)