Logo-aim
Arch Iran Med. 2019;22(6):336-339.
  Abstract View: 47
  PDF Download: 48

Case Report

Evans Syndrome with Acute Kidney Injury

Hanfei Lin 1, Kefei Wu 1, Weidai Zhang 1, Guili Lin 1, Chudan Cai 1 *

1 Department of Nephrology Medicine, The first Affiliated Hospital of Shantou University Medical College, Shantou, China.

Abstract

Evans syndrome is a rare syndrome associated with the simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and idiopathic thrombocytopenic purpura (ITP). Furthermore, acute kidney injury (AKI) is a syndrome characterized by the rapid loss of kidney excretory function and is most often secondary to extrarenal events. However, AKI has rarely been recorded in Evans syndrome without systemic autoimmune disease and malignant tumors of the blood and lymphatic system. Herein, we report the case of a patient who exhibited Evans syndrome presenting with AKI. A 73-year-old woman presented with diarrhea, anuria, low platelet count, and developed a progressive increase of blood urea nitrogen and serum creatinine, as well as anemia with a positive direct Coombs test. We excluded hemolytic uremic syndrome, ITP, and leukemia. Treatment with antibiotics, rehydration therapy, and hemodialysis resulted in partial remission; thus, we diagnosed the patient with Evans syndrome presenting with AKI. The patient was successfully treated by the addition of steroid treatment. When AKI presents with hemolysis and thrombocytopenia, physicians should consider Evans syndrome, which can be appropriately treated when detected early.
Keywords: Acute kidney injury, Evans syndrome
Cite this article as: Lin H, Wu K, Zhang W, Lin G, Cai C. Evans syndrome with acute kidney injury. Arch Iran Med. 2019;22(6):336– 339.
First name
 
Last name
 
Email address
 
Comments
 
Security code


Article Viewed: 47

Your browser does not support the canvas element.


PDF Downloaded: 48

Your browser does not support the canvas element.

Submitted: 17 Jun 2018
Accepted: 16 Apr 2019
First published online: 01 Jun 2019
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - FireFox Plugin)